UTI
1. Introduction
Bacterial infection that affects any part of the urinary tract.
Lower: urethritis, cystitis
Upper: pyelonephritis, renal or perinephric abscess, prostatitis
2. classification
(1). Uncomplicated UTI: acute cystitis (most common) in non-pregnant women without underlying structural or neurological disease
(2). Complicated UTI:
-pregnant
-immunosuppression
-anatomy: VUR, ureter duplication, urolithiasis, tumor, BPH, male
-on Foley catheter
3. microbiology
-Uncomplicated UTI: 80% E. coli
-Complicated UTI: 30% E. coli, 20% enterococci, 20% pseudomonas
-Catheter-associated: 30% yeast, 20% E. coli
-emphysematous APN: DM patients 最多,以E. coli為主
-if treat with anti 後持續fever 3~5 days→小心是Complicated UTI,須做KUB, renal echo
4. symptoms
Upper tract: fever, chills, flank pain, N/V, abdominal pain, diarrhea
<p.s.>chronic prostatitis: 和cystitis症狀類似,加上obstruction 的症狀
Acute prostatitis: perineal pain, fever, tenderness on DRE
Lower tract (ex. acute cystitis): dysuria, urgency, frequency, hematuria, suprapubic pain (通常不會fever)
Young children: diarrhea, loss of appetite, nausea and vomiting, fever, and excessive crying that cannot be resolved by typical measures.
5. Diagnosis
(1). Urinalysis: pyuria+ bacteriuria+/- hematuria
=> bacterial count> 100000 CFU/ml in asymptomatic women, > 1000 CFU/ml in men, > 100 CFU/ml in catheterized patients
=>nitrite: proteus, enterobacteria, K.P., E. coli會產生nitrite,只有25% 會出現反應,但檢測出幾乎就能確定是UTI
=> leukocyte esterase: WBC active 才出現,75% 的敏感性, 陽性反應的話, 有64 % 的機會懷疑有pyuria
(2). Urine gram stain and culture
(3). History:排尿習慣(有無不正常的憋尿) 和排便衛生
(4). Sexual life: r/o STD
6. 比較
symptoms |
+ |
+ |
- |
+ |
- |
pyuria |
+ |
+/- |
+/- |
- |
+ |
bacteria |
+ |
- |
+ |
+/- |
- |
outcome |
1 |
2 |
3 |
4 |
5 |
1: UTI
2: partial treatment(treat with anti), non-bacteria infection
3: asymptomatic bacteriauria→只有 pregency, pre-surgery, immunecomprise (use steroid, chemotherapy patient)才treat
4: neutropenia
5: GN (inflammation)
<p.s.>sterile pyuria: urethritis, renal tuberculosis, foreign body